首页|瓣环与左室流出道椭圆率比值及瓣环离心指数对经导管主动脉瓣置换术治疗的主动脉瓣狭窄病人围术期预后的影响

瓣环与左室流出道椭圆率比值及瓣环离心指数对经导管主动脉瓣置换术治疗的主动脉瓣狭窄病人围术期预后的影响

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目的 探讨主动脉根部因素[瓣环与左室流出道(LVOT)椭圆率比值、瓣环离心指数]对经导管主动脉瓣置换术(TAVR)治疗的主动脉瓣狭窄(AVS)病人围术期预后的影响.方法 选取2016年1月至2022年5月在新疆医科大学第一附属医院行TAVR治疗的AVS病人110例,根据病人瓣环离心指数与瓣环形态的关系,分为离心指数<0.1组65例及离心指数≥0.1组45例,同时根据病人瓣环与LVOT形态的相似程度将病人分为瓣环与LVOT椭圆率比值>1组43例及椭圆率比值≤1组67例,分别比较瓣环离心指数、瓣环与LVOT椭圆率比值对病人围手期预后的影响.结果 不同瓣环离心指数的AVS病人围术期的中/重度瓣周漏率(球囊后扩之前)(15.4%比46.7%,P<0.001)及新发传导阻滞率(32.3%比53.3%,P<0.05)、不同瓣环与LVOT椭圆率比值的AVS病人围术期的新发传导阻滞率(53.5%比32.8%,P<0.05)差异有统计学意义.结论 瓣环与LVOT椭圆率比值>1的TAVR病人有较高的围术期传导阻滞发生率,瓣环离心指数<0.1的TAVR病人有较低的围术期传导阻滞发生率及中/重度瓣周漏率.
Effect of valvular annulus to left ventricular outflow tract ellipticity ratio and valvular annulus centrifugal index on perioperative prognosis of AVS patients undergoing TAVR
Objective To analyze the effect of aortic root factors(valvular annulus to left ventricular outflow tract(LVOT)ellipticity ratio,valvular centrifugation index)on perioperative prognosis of aortic valve stenosis(AVS)patients undergoing transcatheter aortic valve replacement(TAVR).Methods Retrospective analysis was performed on AVS patients who underwent TAVR(110 cases)in The First Affiliated Hospital of Xinjiang Medical University from January 2016 to May 2022.According to the relationship between the flap ring centrifugation index and flap ring morphology,the patients were assigned into a group with a centrifugation index<0.1(n=65)and a group with a centrifugation index≥0.1(n=45).Meahwhile,patients were assigned into valvular annulus to LVOT ellipticity ratio>1 group(n=43)and≤1 group(n=67)according to the similarity of valvular annulus to LVOT morphology.The effects of valvular centrifu-gation index and valvular annulus to LVOT ellipticity ratio on perioperative prognosis were compared.Results Significant differences were found in perioperative rates of moderate/severe perivalvular leakage(15.4%vs.46.7%,P<0.001)(before post-balloon expansion)and new block(32.3%vs.53.3%,P<0.05)in AVS patients with different valvular centrifugation indices,and the perioperative rate of new block in AVS patients with different valvular annulus to LVOT ellipticity ratio(53.5%vs.32.8%,P<0.05).Conclusion The inci-dence of perioperative block was higher in TAVR patients with valvular annulus to LVOT ellipticity ratio>1,and the incidences of peri-operative block and moderate/severe perivalvular leakage were lower in TAVR patients with valvular centrifugation index<0.1.

Aortic valve stenosisTranscatheter aortic valve replacementPerioperative prognosisEllipticity ratioCentrifugal index

吴国良、朱嘉俊、赵龙、陈清杰、李晓梅、杨毅宁

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新疆医科大学第一附属医院心脏中心,新疆维吾尔自治区 乌鲁木齐 830001

新疆维吾尔自治区人民医院心脏中心,新疆维吾尔自治区 乌鲁木齐 830001

主动脉瓣狭窄 经导管主动脉瓣置换术 围术期 椭圆率比值 离心指数

2025

安徽医药
安徽省药学会

安徽医药

影响因子:1.941
ISSN:1009-6469
年,卷(期):2025.29(2)