Analysis of factors influencing delayed hyponatremia after neuroendoscopic transs-phenoidal surgery for pituitary adenoma
Objective To investigate the factors influencing and treatment of delayed hyponatremia after neuroendoscopic transsphe-noidal surgery for pituitary adenoma.Methods A retrospective analysis of 270 patients with pituitary adenoma treated by neuroendo-scopic transsphenoidal surgery at the Affiliated Hospital of Xuzhou Medical University from January 2020 to March 2023 were selected and clinical,laboratory and imaging data were recorded to determine the factors influencing postoperative delayed hyponatremia by uni-variate and multifactorial logistic analysis.Results Of the 270 patients,50 developed postoperative delayed hyponatremia,with an in-cidence of 18.5%,occurring between the 5th and 7th postoperative day.Multi-factorial logistic regression analysis showed that patients with significant preoperative and postoperative changes in saddle diaphragm height,large changes in the angle of tilt of the pituitary stalk,large changes in the length of the"measurable pituitary stalk",small postoperative pituitary stalk tilt,no diabetes insipidus and long hospital stays were at greater risk of developing delayed hyponatraemia(P<0.05).Conclusion Changes in saddle diaphragm height,pituitary stalk tilt angle and"measurable pituitary stalk"length before and after surgery play an important role in predicting de-layed hyponatremia after neuroendoscopic transsphenoidal surgery for pituitary adenoma.
万方数据
维普
