Objective:To study the efficacy of Bailing Capsule in the treatment of early peritoneal dialysis(EPD)patients.Methods:A total of 100 EPD patients treated in Yichang Central People's Hospital from January 2019 to December 2020 were randomly divided into two groups using a random number table method.The control group received EPD treatment(n=50),while the observation group received EPD treatment plus Bailing Capsule(n=50).Renal function,nutritional status,micro-inflammatory factors,and oxidative stress indicators were compared between the two groups after three months of treatment.Results:In terms of improving renal function,the residual renal function(RRF),24-hour urine volume,and 24-hour ultrafiltration volume were significantly higher in the observation group than in the control group(all P＜0.05).In terms of nutritional status,serum albumin(Alb),prealbumin(PA),transferrin(TRF),and hemoglobin(Hb)were significantly higher in the observation group than in the control group(all P＜0.05),and the modified quantitative subjective global assessment(MQSGA)was significantly lower in the observation group(10.02±1.05 vs 12.54±2.20,P＜0.05).In terms of micro-inflammatory markers,serum levels of interleukin 6(IL-6),tumor necrosis factor-α(TNF-α),hypersensitive C-reactive protein(hs-CRP),vascular endothelial growth factor(VEGF),and transforming growth factor-β1(TGF-β1)were significantly lower in the observation group than in the control group(all P＜0.05).In terms of oxidative stress,serum levels of malondialdehyde(MDA)and homocysteine(Hcy)were significantly lower in the observation group than in the control group,while superoxide dismutase(SOD)activity was significantly higher in the observation group(all P＜0.05).There was no significant difference in adverse reactions between the two groups(P＞0.05).Conclusion:Bailing Capsule can effectively alleviate oxidative stress and micro-inflammatory status,improve malnutrition,and enhance renal function in EPD patients.
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