Acute pulmonary thromboembolism(PTE),with its insidious onset,acute morbidity,severe symptoms,and high mortality,is the third most common cardiovascular disease worldwide.Current treatment modalities for acute PTE include anticoagulation,thrombolysis,percutaneous endovascular aspiration,and surgical thrombectomy.Anticoagulation is generally preferred for hemodynamically stable PTE,and anticoagulation and systemic thrombolysis are generally recommended for hemodynamically unstable PTE,but the high risk of bleeding and limited efficacy of thrombolysis are gradually being replaced by percutaneous endovascular aspiration.AngioJet mechanical thrombus aspiration provides rapid thrombus removal,reduces pulmonary artery pressure,improves right heart function,and corrects hypoxemia,significantly improving patient quality of life and survival.This article describes the surgical procedure of AngioJet mechanical thrombus aspiration for the treatment of PTE and discusses potential intraoperative problems and solutions.