When patients are admitted to the hospital in critical condition,their bodies undergo stress which leads to the release of a large number of cytokines and neuroendocrine disorders.This often causes stress-induced hyperglycemia(SIH).SIH can result in disturbances in water,electrolyte,and acid-base balance,as well as an increased risk of infection.Continuous intravenous insulin infusion is commonly recommended in clinical practice to regulate blood glucose levels.However,improper use of insulin therapy may lead to hypoglycemia.Blood sugar fluctuations in patients can increase glycemic variability(GV)and exacerbate oxidative stress-induced inflammatory responses.This can cause damage to the immune system and vascular endothelial function in critically patients,posing a threat to their lives.In summary,glycemic management is crucial for critically patients.This review summarizes the latest advances in glycemic management in critically patients,mainly from the impact and mechanism of glycaemia on the prognosis of critically patients,and glycaemic management measures.The objective is to provide a reference for the management of blood glucose in critically patients.