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中医药通过调节肠道菌群防治心力衰竭的研究进展

Research Progress on Prevention and Treatment of Heart Failure by Regulating Intestinal Flora with Traditional Chinese Medicine

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肠道菌群失调存在于心力衰竭(HF)的患者中,HF患者肠壁通透性增加,肠道微生物群以及代谢物紊乱,继而发生炎症反应促进HF进一步加重.中医药可以通过调节肠道细菌代谢产物氧化三甲胺(TMAO)防治HF.本文基于"心-肠轴"的经典理论,结合现代医学知识,探讨中医药通过调节肠道菌群防治HF的研究现状及前景.
Intestinal flora imbalance exists in patients with heart failure(HF).In HF patients,intestinal wall permeability increases,intestinal microbiota and metabolites are disturbed,and then inflammation occurs to further aggravate HF.Traditional Chinese medicine can prevent and treat HF by regulating intestinal bacterial metabolites(TMAO).Based on the classical theory of"heart and small intestine"and modern medical knowledge,this paper discusses the research status and prospect of traditional Chinese medicine in the prevention and treatment of chronic HF by regulating intestinal flora.

intestinal floraheart failure(HF)traditional Chinese medicine treatmenttrimethylamine oxide(TMAO)

李豫、卢超、王运华、谭熊瑶、张继红

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三峡大学附属第二人民医院中西医结合心血管科,湖北宜昌 443000

三峡大学附属中医医院心病科,湖北 宜昌 443003

肠道菌群 心力衰竭 中医治疗 氧化三甲胺

2024

巴楚医学
三峡大学

巴楚医学

ISSN:2096-6113
年,卷(期):2024.7(4)