首页|Neurotransmitter-mediated artificial synapses based on organic electrochemical transistors for future biomimic and bioinspired neuromorphic systems

Neurotransmitter-mediated artificial synapses based on organic electrochemical transistors for future biomimic and bioinspired neuromorphic systems

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Neurotransmitter-mediated artificial synapses based on organic electrochemical transistors for future biomimic and bioinspired neuromorphic systems
Organic electrochemical transistors have emerged as a solution for artificial synapses that mimic the neural func-tions of the brain structure,holding great potentials to break the bottleneck of von Neumann architectures.However,current artificial synapses rely primarily on electrical signals,and little attention has been paid to the vital role of neurotransmitter-medi-ated artificial synapses.Dopamine is a key neurotransmitter associated with emotion regulation and cognitive processes that needs to be monitored in real time to advance the development of disease diagnostics and neuroscience.To provide insights into the development of artificial synapses with neurotransmitter involvement,this review proposes three steps towards future biomimic and bioinspired neuromorphic systems.We first summarize OECT-based dopamine detection devices,and then review advances in neurotransmitter-mediated artificial synapses and resultant advanced neuromorphic systems.Finally,by exploring the challenges and opportunities related to such neuromorphic systems,we provide a perspective on the future devel-opment of biomimetic and bioinspired neuromorphic systems.

artificial synapsesorganic electrochemical transistorsneurotransmittersneuromorphic systems

Miao Cheng、Yifan Xie、Jinyao Wang、Qingqing Jin、Yue Tian、Changrui Liu、Jingyun Chu、Mengmeng Li、Ling Li

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Key Lab of Fabrication Technologies for Integrated Circuits,Chinese Academy of Sciences,Beijing 100029,China

Institute of Microelectronics,Chinese Academy of Sciences,Beijing 100029,China

University of Chinese Academy of Sciences,100049 Beijing,China

artificial synapses organic electrochemical transistors neurotransmitters neuromorphic systems

2025

半导体学报(英文版)
中国电子学会和中国科学院半导体研究所

半导体学报(英文版)

影响因子:0.36
ISSN:1674-4926
年,卷(期):2025.46(1)