Taking the honeysuckle as the experimental material,sodium selenite was sprayed on its leaves.High performance liquid chromatography and UV spectrophotometry were used,the effect of exogenous selenium on the content of effective components in honeysuckle leaves was studied,in order to promote the comprehensive utilization of selenium rich honeysuckle and explore broader prospects for the development of honeysuckle into food or medicine.The results showed that when the concentration of sodium selenite was within 10,20,50,and 100 mg·L-1,it promoted the growth of honeysuckle.When the concentration of sodium selenite was 10 mg·L-1,the content of chlorogenic acid was as high as 1.06%;the soluble sugar content was as high as 1.51%;the soluble protein content was 32.51 mg·g-1,with an increase of 33.62%,57.29%,and 27.49%compared to the CK,respectively.When the concentration of sodium selenite was 50 mg·L-1,the contents of isochlorogenic acid A,isochlorogenic acid C,and vitamin C reached their peak values of 1.36%,0.95%,and 0.73 mg·g-1,respectively.At this time,the concentration increased by 20.80%,4.58%,and 58.69%compared to the CK,respectively.When the concentration of sodium selenite was 100 mg·L-1,the maximum value of luteolin was 1.66%,which was 40.19%higher than the CK.In summary,the appropriate concentration of sodium selenite had a certain promoting effect on the growth of honeysuckle,which helped to synthesize and accumulate effective ingredients in honeysuckle leaves,thereby improving the quality of honeysuckle's medicinal and edible dual-use.