A Study on HCV Genotypes of 259 Hepatitis C Virus Patients in Guangzhou Area
Objective To understand the distribution of HCV genotypes in patients with hepatitis C virus in Guangzhou area,and to provide a knowledge basis for the prevention and treatment of hepatitis C virus. Methods We obtained the results of HCV genotypes of 259 hepatitis C virus patients from September,2019 to April,2023,and compared positive rates of various genotypes across different age,gender groups and years. Results A total of 259 patients were included and the most common genotypes were 6a and 1b,accounting for 42.47％ and 42.08％ respectively.There were statistically significant differences when compared with other subtypes (P<0.05).Following these genotypes,others were 3a (6.18％),2a (4.63％),3b (4.25％)and 2b (0.39％).No mixed infection was found.The positive rates of 1b in young people (41.86％)and middle-aged people (31.447％)were lower than that of 71.93％ in the elderly.The positive rates of 6a in young people (44.186％)and middle-aged people (51.572％)were higher than that of 15.789％ in the elderly, with statistical differences.The positive rates of 1b (63.077％)and 2a (10.769％)in females were higher than that of 35.052％and 2.577％in males,respectively.The positive rates of 6a in females (18.462％)were lower than that of 50.516％ in males,with statistical differences.There was no statistical difference between different years.Conclusion HCV genotypes of hepatitis C virus patients in Guangzhou area are mainly 6a and 1b.1b is more common in elderly people and female.6a is the predominant genotype among young and middle-aged population and males.
万方数据
维普
