An Analysis of Allergen Specific IgE Detection Results in 528 Children with Allergic Rhinitis
Objective To better understand the common allergens and their distribution characteristics of allergic rhinitis in children in our hospital in recent years,and to provide a clinical reference basis for the prevention and treatment of allergic rhinitis in children.Methods Serum samples of 528 children with allergic rhinitis admitted to our Otorhinolaryngology Department from March,2020 to March, 2022 were tested for 29 allergens,then grouped according to gender and age,and the results were statistically analyzed.Results The total positive rate of allergens was 78.79%.Among all rates,the overall positive rates were 73.30% for inhalant allergens and 31.82% for ingestive allergens.The top three inhalant allergen positivity rates were house dust mite,dermatophagoides farinae,and blomia tropicalis.The top three positive rates of ingested allergens were milk,shrimp/crab,and egg white. The allergen positive rate was 81.01% in boys and 74.12% in girls.The positive rates of dermatophagoides farinae,blomia tropicalis, feline fur crumbs, gramineous/Ryegrass/echelon forages in June,and egg white were significantly different among different age groups(P<0.05). Conclusion Inhalant allergens in children with allergic rhinitis are mainly house dust mites, dermatophagoides farinae,and blomia tropicalis;Ingested allergens are mainly milk,shrimp/crab, and egg whites.Allergen specific IgE testing can help to better understand the allergy profile in children with allergic rhinitis.