首页|528例变应性鼻炎患儿过敏原特异性IgE检测分析

528例变应性鼻炎患儿过敏原特异性IgE检测分析

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目的 了解我院近年儿童变应性鼻炎常见过敏原及其分布特征,为儿童变应性鼻炎的预防和治疗提供临床依据.方法 对我院耳鼻喉科2020年3月至2022年3月门诊收治528例变应性鼻炎患儿的血清进行过敏原29项检测,依据性别、年龄进行分组,并对多因素应用卡方检验进行统计分析.结果 过敏原总阳性率为78.79%.其中吸入性过敏原总阳性率为73.30%,食入性过敏原总阳性率为31.82%.吸入性过敏原阳性率前3位分别为户尘螨、粉尘螨、热带无爪螨.食入性过敏原阳性率前三位分别为牛奶、虾/蟹、鸡蛋白.男童过敏原阳性率为81.01%,女童敏原阳性率为74.12%.户尘螨、粉尘螨、热带无爪螨、猫毛皮屑、鸡蛋白阳性率在不同年龄之间差异有统计学意义(P<0.05).结论 我院儿童变应性鼻炎吸入性过敏原以户尘螨、粉尘螨、热带无爪螨为主;食入性过敏原以牛奶、虾/蟹、鸡蛋白为主.过敏原特异性IgE检测有助于了解变应性鼻炎患儿的过敏情况.
An Analysis of Allergen Specific IgE Detection Results in 528 Children with Allergic Rhinitis
Objective To better understand the common allergens and their distribution characteristics of allergic rhinitis in children in our hospital in recent years,and to provide a clinical reference basis for the prevention and treatment of allergic rhinitis in children.Methods Serum samples of 528 children with allergic rhinitis admitted to our Otorhinolaryngology Department from March,2020 to March, 2022 were tested for 29 allergens,then grouped according to gender and age,and the results were statistically analyzed.Results The total positive rate of allergens was 78.79%.Among all rates,the overall positive rates were 73.30% for inhalant allergens and 31.82% for ingestive allergens.The top three inhalant allergen positivity rates were house dust mite,dermatophagoides farinae,and blomia tropicalis.The top three positive rates of ingested allergens were milk,shrimp/crab,and egg white. The allergen positive rate was 81.01% in boys and 74.12% in girls.The positive rates of dermatophagoides farinae,blomia tropicalis, feline fur crumbs, gramineous/Ryegrass/echelon forages in June,and egg white were significantly different among different age groups(P<0.05). Conclusion Inhalant allergens in children with allergic rhinitis are mainly house dust mites, dermatophagoides farinae,and blomia tropicalis;Ingested allergens are mainly milk,shrimp/crab, and egg whites.Allergen specific IgE testing can help to better understand the allergy profile in children with allergic rhinitis.

ChildrenAllergic rhinitisAllergens

周芬、刘彪、陈金妮

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海南省妇女儿童医学中心检验科,海南 海口 570206

儿童 变应性鼻炎 过敏原

海南省自然科学基金面上项目海南省临床医学中心建设项目

821MS145琼卫函[2021]75号

2024

标记免疫分析与临床
中国同辐股份有限公司

标记免疫分析与临床

CSTPCD
影响因子:0.978
ISSN:1006-1703
年,卷(期):2024.31(1)
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