Protein disulfide isomerase has the biological activity of enzyme and molecular chaperone, and can play an important role in the process of protein synthesis and secretion.This article reviews the recent research progress of its molecular structure, biological function and its underlying functional mechanism in the occurrence and development of thrombotic diseases, tumors and neurodegenerative diseases.
关键词
蛋白质二硫键异构酶/血栓性疾病/肿瘤/神经退化性疾病
Key words
Protein disulfide isomerase/Thrombotic disease/Tumor/Neurodegeneration disease