An Analysis of Risk Factors for Recurrence of Acute Cerebral Infarction
Objective To investigate the relationship between lipoprotein-associated phospholipase A2(Lp-PLA2)and soluble lectin-like oxidized low density lipoprotein receptor 1(sLOX-1)on recurrence of acute cerebral infarction and TOAST classification.Methods 181 patients with acute cerebral infarction(ACI)admitted to our hospital from July,2021 to January.2023 and 154 healthy control groups were selected for the study.Patients with ACI were divided into the first onset and recurrence according to their medical history,and large atherosclerosis type(LAA)and small artery occlusion type(SAO)according to TOAST classification.Levels of Lp-PLA2 and sLOX-1 were compared among all groups.Logistic regression was performed to analyze the risk factors of recurrent acute cerebral infarction.Results Levels of Lp-PLA2 and sLOX-1 in ACI were significantly higher than those in the healthy control group;The Lp-PLA2 and sLOX-1 levels in the recurrent group were significantly higher than those in the first onset group;The level of sLOX-1 in the LAA group was significantly higher than that in SAO.There was no difference in Lp-PLA2 between the two groups.Conclusion Lp-PLA2 and sLOX-1 can serve as indicators for predicting acute cerebral infarction,and are risk factors for recurrence of acute cerebral infarction.sLOX-1 is also associated with the etiology of acute cerebral infarction.
NETL
NSTL
万方数据
维普
