The Research Progress on the Relationship Between Autophagy and Diabetic Nephropathy
The pathogenesis of diabetic nephropathy(DN)remains unclear.Autophagy is a ubiquitous life phenomenon in eukaryotes,and its main function is to maintain the homeostasis of intracellular environment by decomposing and reusing intracellular proteins and removing damaged organelles.Recent studies have shown that autophagy could play a key role in the pathogenesis of DN.This paper reviews the current research progress of autophagy in DN,and discusses its prevention and treatment of DN,in order to provide an updated theoretical basis for a wide range of targeted therapy options and related clinical practice.
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万方数据
维普
