A Study of Monitoring Effect of Anti-Xa Factor on Anticoagulation Administration in High-risk Patients
Venous thromboembolism(VTE)is a world-wide public health problem.Due to its high incidence rate and mortality,many prevention and treatment guidelines for VTE at home and abroad have been proposed for prevention purpose,but VTE events remain as a significant issue.Low molecular weight heparin(LMWH)is currently the primary choice for anti-coagulation in clinical practice.Monitoring its anti-coagulant efficacy can reduce the risk of thrombosis.Previous research has shown that the level of anti-Xa activity can effectively evaluate the anti-coagulant effect of LMWH,This article reviews the role of anti-Xa,an indicators in preventive anti-coagulant therapy in special populations,and evaluates the safety and effectiveness of anti-Xa for monitoring anti-coagulant therapy.