An Analysis of Antibiotic Resistance and Homology of Acinetobacter Baumannii in Our Hospital
Objective To better understand the clinical infection characteristics,drug resistance and homology of A.baumannii in our inpatients and the environment,and to provide reference for effective clinical treatment and infection control and prevention.Methods A total of 824 strains of Acinetobacter baumannii isolated from selected departments and related environments of our hospital from November,2018 to June,2021 were collected,among which 47 strains of Acinetobacter baumannii suspected of cross infection in key departments were collected.We used Vitek-compact automatic microbial analysis system for strain identification and drug susceptibility test,and multi-site sequence typing and matrix assisted laser resolved ionization time mass spectrometry (MALDI-TOF MS)for homology analysis.Results 47 A.baumannii were susceptible to colistin,with 89.5％, 80.0％ and 56.6％ for cefoperazone and sulbactam.36 showed antibiotic resistance,76.6％ for MDRAB,and 8 sequence types of ST2 (38,80.8％)were identified,followed by ST10 (2,4.3％)and ST132 (2,4.3％).The distribution characteristics were mainly in Respiratory and Critical Care Medicine,Intensive Care Medicine and Neurosurgery wards.Conclusion The resistance rate of Acinetobacter baumannii in our hospital is high.Several clonal strains are widely distributed in the hospital,and there is a close kinship relationship in some departments,which indicates that the prevention and control of hospital infection should be further strengthened.
万方数据
维普
