Objective To analyze characteristics of bacterial identification and drug resistance among inpatients at Beijing Rehabilitation Hospital in 2022.Methods Throughout 2022,a retrospective analysis was conducted on non-repetitive bacterial strains isolated from inpatients at Beijing Rehabilitation Hospital.The drug susceptibility of these strains was determined based on the 2022 CLSI M100 standard.The collected data were analyzed using WHONET5.6 software.Results By the year 2022,the microbiological laboratory successfully isolated a total of 1946 distinct bacterial strains,out of which 1552 were Gram negative bacteria,constituting 79.8％ of the total,while 394 strains were Gram positive bacteria,representing 20.2％.Klebsiella pneumoniae,Pseudomonas aeruginosa,Escherichia coli,and Acinetobacter baumannii were the four most common types of Gram-negative bacteria.Gram positive bacteria mainly included Enterococcus and Staphylococcus.A total of 183 strains of Enterococcus were identified.Among 194 strains of Staphylococcus,coagulase negative Staphylococcus was found to be more common than Staphylococcus aureus.The main types of specimens were urine and sputum samples, while blood samples only made up 9.7％.The Neurological Rehabilitation Center had the highest number of isolated bacterial strains,accounting for 30.3％.Klebsiella pneumoniae displayed the highest resistance rate towards carbapenem antibiotics.Pseudomonas aeruginosa exhibited high sensitivity towards amikacin,with a resistance rate below 10％.The resistance rates to imipenem and meropenem were 45.2％ and 35.6％, respectively.Acinetobacter baumannii demonstrated the highest susceptibility to tigecycline.In contrast,the resistance rates for other commonly utilized antibiotics exceed 50％.Enterococcus faecalim showed a significantly elevated resistance rate of 33.3％ against vancomycin,whereas Enterococcus faecalis displayed a mere 1 .4％ resistance rate.The detection rate of methicillin resistant Staphylococcus aureus (MRSA)was 61.6％,while coagulase negative Staphylococcus (MRCNS)had a detection rate of 89.8％.No vancomycin resistant Staphylococcus was found. Conclusion The predominant bacteria found in our hospital belong to the Gram-negative category, and its drug resistance is exceptionally severe.It is very important to monitor bacterial resistance and strengthen the management of hospital-level infections.
关键词
耐药性/细菌耐药监测/抗菌药物
Key words
Drug resistance/Surveillance of bacterial resistance/Antibiotics
维普
万方数据