The Clinical Application Value of 99Tcm-MIBI SPECT/CT Myocardial Imaging in COVID-19 Patients with Concurrent Myocarditis
Objective This study aims to evaluate the clinical application value of 99 Tc m-MIBI SPECT/CT gated myocardial perfusion imaging (G-MPI)in the diagnosis of myocarditis concurrent with COVID-19.Methods A retrospective analysis was conducted on the results of 99 Tc m-MIBI SPECT/CT MPI examinations performed on patients diagnosed with COVID-19 from December,2022 to February,2023.Comparisons were performed among myocarditis patients in terms of gender,age,severity of COVID-19,myocardial enzyme levels,and cardiac functional parameters.Results Among 86 COVID-19 patients,51 (59.30％) developed concurrent myocarditis.99 Tc m-MIBI G-MPI images primarily showed"mottled"changes, indicating irregular and scattered distribution of the tracer with sparse and reduced uptake.Among these,32 patients (62.75％)exhibited involvement of all walls of the left ventricle.The condition of left ventricular walls in MPI was closely related to the occurrence of myocarditis,particularly in the inferior,anterior, lateral,and apical walls (P<0.001).Age was negatively correlated with the risk of myocarditis (-0.360, P<0.001),while the severity of COVID-19 was positively correlated with the risk (0.244,P=0.024). There was no significant correlation between gender,myocardial enzymes,and cardiac functional parameters (EDV,ESV,LVEF)with the occurrence of myocarditis (P>0.05 ).Conclusion COVID-19 can cause myocarditis,which increases with severities of the disease.The primary group affected by this is middle-aged and elderly patients,though the risk slightly decreases with advancing age.Gender,myocardial enzyme levels,and cardiac functional parameters show no significant correlation with myocarditis.99 Tc m-MIBI SPECT/CT myocardial imaging has a high clinical value in the precise diagnosis of myocarditis concurrent with COVID-19 and is recommended for general clinical practices.
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