A Study of the Clinical Distribution and Drug Resistance of Klebsiella Pneumoniae Isolated From a Hospital From 2016 to 2022
Objective To analyze the change of drug sensitivity of Klebsiella pneumoniae isolated in our hospital from 2016 to 2022,so as to guide clinical rational drug use and control for the infection caused by Klebsiella pneumoniae.Methods Klebsiella pneumoniae isolated from clinical patients during 2016-2022 were cultured,and then tested for drug sensitivity.The data of antimicrobial susceptibility rate in key departments and hospitals with Klebsiella pneumoniae infection were analyzed retrospectively.Results From 2016 to 2022,17,827 strains of pathogenic bacteria were isolated,of which 2963(16.6％)were Klebsiella pneumoniae.The detection rate increased from 16.4％ to 34.8％in Intensive Care Unit (ICU ).The detection rate of Departments of Respiratory Medicine,Neurology and Geriatrics was about 20％.The detection rate of Extended-spectrum β-lactmase (ESBL)in Klebsiella pneumoniae was 15％ -25％.The sensitivity of Klebsiella pneumoniae to antibiotics decreased from 59.8％ to 28.8％ in ICU,while rates for the other three key departments:Respiratory Medicine,Neurology,Geriatrics Medicine in the strain of drug sensitivity were not significantly different.Conclusion Klebsiella pneumoniae is an important Clinical strains from clinical samples in our hospital.Changes of drug sensitivity of Klebsiella pneumoniae in vitro are closely related to clinical medication,treatment,prognosis of patients and control of medical cost.The hospital should strengthen its surveillance,prevention and infection control.
Klebsiella pneumoniaeCarbapenem-resistant Klebsiella pneumoniaeDrug sensitivity testClinical rational use
万方数据
维普
