Objective To investigate clinical characteristics,as well as the status of diagnosis and treatment,and prognosis of acute eosinophilic pneumonia (AEP)after SARS-CoV-2 infection.Methods On June 15,2023,a patient with acute eosinophilic pneumonia after SARS-CoV-2 infection admitted to Xingtai People 's Hospital affiliated to Hebei Medical University was selected as the research object.This patient was then followed up until December 15th,2023.We used a retrospective analysis method for a comprehensive analysis,by combining the clinical data of this patient and cases previously reported in domestic and foreign literatures.Results The studied patient was a 77-year-old male.At first,there was no obvious cause of fever,cough,expectoration and asthma,and PCR for SARS-CoV-2 was positive.The effect of anti-inflammatory and anti-infective treatment in the external hospital was poor.On June 15th,2023,the patient was admitted to the Respiratory Department of our hospital with"pneumonia"for treatment.Chest CT showed pneumonia in the lower lobe of the right lung and bilateral pleural effusion.Symptomatic treatments,such as anti-infection,were not effective,and 42% of eosinophils were found in bronchoalveolar lavage fluid (BALF).Acute eosinophilic pneumonia was considered,and treatment with glucocorticoids on the basis of anti-infection showed improved effects.The follow-up was conducted until December 15th,2023,and there was no recurrence of the patient's condition.Conclusion COVID-19 can trigger AEP in rare cases,and AEP can be used as a differential diagnosis for COVID-19 infected patients,especially those with poor anti-infection treatment effects.