The Predictive Value of Routine Physical Examination Indicators for the Occurrence of Carotid Atherosclerosis
Objective To explore the predictive value of routine physical examination indicators,such as gender,age,blood pressure,blood lipids,and homocysteine in the occurrence of carotid atherosclerosis.Methods A retrospective cohort study method was applied for this analysis.985 individuals who underwent health examinations in our hospital for 6 consecutive years from January,2016 to December,2021 were selected as the research subjects.We collected general information,physical examination indicators,laboratory examination indicators,carotid ultrasound results,and other information from these subjects.During follow-up,if the subjects were diagnosed with carotid intima-media thickness (cIMT)>1 mm or carotid plaque formation by carotid ultrasound,they were considered to have carotid atherosclerosis progression and the follow-up ended.If there was no progression of carotid atherosclerosis,those subjects were followed up until December 2021.We divided the study subjects into the sclerosis group,progression group,and control group based on whether cIMT increased during follow-up.We then analyzed the influencing factors of carotid atherosclerosis occurrence and used subject operating characteristic curves to evaluate the diagnostic efficacy of physical examination indicators for carotid atherosclerosis.Results In the progression group,TC,LDL-C,FBG,UA,Hcy and SBP were higher than before the onset of carotid atherosclerosis,while HDL-C was lower than before the onset,with statistical significance (P<0.05);The sclerosis group had no statistically significant differences in HDL-C and Hcy indicators,while other indicators,such as male proportion,age,TC,TG,LDL-C,FBG,UA,SBP,DBP and BMI,were higher than the control group,with statistical significance (P<0.05);Among them,FBG,LDL-C,and SBP were independent risk factors for the occurrence of carotid atherosclerosis (OR=5.505,4.222,1.071,P<0.05).The area under the curve for the combined diagnosis of carotid atherosclerosis was higher than that of individual tests,and the difference was statistically significant (P<0.01).Conclusion FBG,LDL-C and BMP are closely related to the occurrence of carotid atherosclerosis,and combined detection has a good diagnostic efficacy for carotid atherosclerosis.
万方数据
维普
