A Validation of Reference Intervals of Clinical Biochemistry Tests Commonly Used for Children in Lhasa Area
Objective To validate the industry standard WS/T780-2021"Reference intervals of clinical biochemistry tests commonly used for children"and to determine whether the standard is applicable to children in Lhasa area.Methods Healthy children from Physical examination population in Lhasa People 's Hospital were selected as reference individuals.According to the gender and age classification standards when establishing reference intervals,at least 20 qualified reference individuals were selected for each subgroup.We collected samples according to WS/T661"Guidelines of venous blood specimen collection".The blood samples were detected by MINDRAY BS2000 automatic biochemical analyser.We compared the detection results with the Industry standard reference intervals and also compared test results between different age and gender subgroups.Results The coincidence rate of ALP in girls aged 17-18 was 73.6％.The coincidence rate of other subgroups was over 90％.In age analysis,except for Cl,all other parameters showed age differences (P<0.05).In gender analysis,AST aged 13-18 and IP aged 15-18 was not statistically significant,while all other parameters showed gender differences (P < 0.05 ).Conclusion"Reference intervals of clinical biochemistry tests commonly used for children"is generally applicable to children in Lhasa area.Reference intervals of ALP in girls aged 17-18 should be redefined.There are significant differences in biochemistry tests for children among different ages and genders.Laboratories should pay attention to age and gender division when citing or establishing reference intervals of biochemical testing for children.
万方数据
维普
