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木村病伴肾病综合征1例

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目的 探讨木村病伴肾病综合征的临床特征,提高对木村病的认识.方法 回顾性分析2023年7月广东省人民医院收治的1例木村病伴肾病综合征患者的临床资料,实验室、影像学、病理检查和骨髓活检结果及诊疗情况并结合最新文献复习,以提高对木村病的认识.结果 男性患者,37岁,既往肾病综合征17年.临床表现为蛋白尿、颈部多发增大淋巴结、皮疹伴瘙痒感.肾穿刺活检符合肾小球微小病变,术后病理结果符合木村病.患者手术切除后口服皮质类固醇结合免疫抑制剂治疗,症状有所改善.结论 木村病患者的肾损害多表现为肾病综合征,少数可早于木村病前出现,对于符合手术指征的患者手术切除联合药物治疗有助于改善病情.
A Case Report of Kimura Disease with Nephrotic Syndrome
Objective To explore clinical characteristics of Kimura disease with nephrotic syndrome and to improve our understanding.Methods A retrospective analysis was conducted on the clinical data,laboratory,imaging,pathological examination,bone marrow biopsy results,diagnosis and treatment information of the patient with Kimura disease and nephrotic syndrome admitted to Guangdong Provincial People's Hospital in July,2023.The latest literature review was conducted and combined to improve our understanding of Kimura disease.Results A 37-years old male patient had multiple enlarged lymph nodes in the neck and a history of nephrotic syndrome for 17 years.The clinical manifestations were proteinuria,rash and itching.The renal biopsy was consistent with minimal glomerular lesions.Postoperative pathological results were consistent with Kimura disease.Patient's symptoms had improved after surgical resection followed by oral corticosteroids combined with immunosuppressants.Conclusion Renal damage in patients with Kimura disease often manifests as nephrotic syndrome,with a few appearing earlier than Kimura disease.Surgical resection combined with medication treatment can help improve the condition for patients.

Kimura diseaseEosinophilsIgENephrotic syndrome

张娟、姚亚男、温魏棋、李文敏

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南方医科大学附属广东省人民医院(广东省医学科学院)检验科,广东 广州 510080

广州南方学院,广东 广州 510970

木村病 嗜酸性粒细胞 IgE 肾病综合征

国家自然科学基金

82202627

2024

标记免疫分析与临床
中国同辐股份有限公司

标记免疫分析与临床

CSTPCD
影响因子:0.978
ISSN:1006-1703
年,卷(期):2024.31(4)
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