A Study for the Clinical Value of the Thromboelastography and Caprini Risk Evaluation-model in Deep Vein Thrombosis of Fracture Patients
Objective To evaluate the clinical predictive value of the risk of deep vein thrombosis(DVT)in patients with traumatic fractures by the thromboelastography(TEG)and Caprini risk assessment model(CapriniRAM).Methods 400 patients with traumatic fractures were collected from June,2022 to April,2023 for the current study.According to the results of color doppler ultrasonography(CDFI)during hospitalization period,those patients were divided into DVT group(63 cases)and non-DVT group(337 cases).We then evaluated the differences of routine coagulation test items,TEG and CapriniRAM scores between the two groups.The diagnostic value of single and combined multiple indicators were also analyzed by receiver operating characteristic(ROC)curve.Results Except for gender ratio,APTT,and PLT,the differences of other analyzed indicators between the two groups were statistically significant(P＜0.01):R and K values significantly decreased in the DVT group,while MA,Angle,CI,and CapriniRAM scores were significantly increased.Multivariate logistic regression analysis showed that after adjusting for confounding factors such as Age,R,Angle,CI,TT,FIB,and DD,K,FDP,and CapriniRAM scores were independent influencing factors for the occurrence of DVT(P＜0.05);AUC of DVT diagnosis based on the combination of the three indicators was 0.890(0.850-0.930),which was significantly higher than that of each single indicator.With the increase of the K value,the incidence of DVT decreased gradually(x2=17.872,P＜0.001),while with the increase of FDP level and CapriniRAM scores,the incidence of DVT gradually significantly increased(x2=58.950,64.827,P＜0.001).Conclusion Low K values,high level of FDP and high Caprini RAM scores are potential risk factors for DVT in patients with traumatic fractures,and the combined multiple indicators can significantly improve the diagnostic efficiency.
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