A Case of Systemic Lupus Erythematosus with Multi-system Involvement Presenting with Bilateral Lower Limb Weakness as the First Manifestation
Systemic lupus erythematosus(SLE)is an autoimmune disease with multi-system involvement and diverse clinical manifestations.Most of SLE patients present to the hospital with symptoms of organ-or system-based involvements.Currently,there are few cases of SLE with multi-system involvements in which bilateral lower extremity weakness is identified as the first clinical manifestation.In this paper,we report a case of 20 years old of SLE with bilateral lower extremity weakness as the first manifestation,accompanied by muscle damage,hematologic involvement,antiphospholipid syndrome(APS),and hepatic involvement.Our results can provide a useful reference for the clinical diagnosis of SLE.
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