The Pathological and Clinical Characteristics of 11 Cases of Autoimmune Gastritis
Objective To investigate the clinical and pathological features of autoimmune gastritis,and to strengthen the interrelation,so as to further improve the timeliness and accuracy of diagnosis. Methods The clinical and pathological features of 11 AIG patients of our hospital were collected and analyzed according to previous literatures.Results The selected patients included 8 females and 3 males,ranging in age from 31 to 78 years,with a median age of 53 years.The clinical manifestations were nonspecific and there were 3 cases with Helicobacter Pylori infection;The atrophy was most common in the body of stomach,followed by the fundus of stomach;4 cases were accompanied by anemia,and 3 of them were accompanied by neuroendocrine cell proliferative lesions;It took 3 years for 1 patient to develop anemia symptoms and to be diagnosed as AIG under the guidance of a pathologist.Conclusion The clinical symptoms,endoscopic and pathological manifestations of AIG patients are different individually,and the endoscopic manifestations are not specific,which can easily cause miss diagnosis.It is recommended to perform routine biopsy in suspected cases of fundus and body mucosa atrophy.In particular,gastric body mucosal biopsy is of great value in the diagnosis of AIG.Anemia with neuroendocrine cell proliferative lesions and atrophy with neuroendocrine cell proliferative lesions are highly suggestive of AIG diagnosis.
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