The Research Progress on Al18F Labeled Biomolecules
In the recent research progress of positron emission tomography (PET)isotopes,the 18F isotope is becoming the preferred isotope for labeling bioactive molecules due to its excellent physical and nuclear properties.Compared to traditional 18F isotope labeling methods,the Al18F complex labeling method combines the favorable decay characteristics of 18F with the convenience and ease of operation based on metal radiolabeling,demonstrating unique advantages in the clinical development and application of radiopharmaceuticals.This article comprehensively reviews the latest research progress of Al18F-labeled bioactive molecules and outlines the current applications and future potential trends of Al18F-labeled biomolecules in various disease areas.