首页|MOFs材料吸附放射性碘核素的研究进展

MOFs材料吸附放射性碘核素的研究进展

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放射性同位素是核医学诊断和治疗的基础,随着国内碘-131(131Ⅰ)类放射性药品使用量的急剧增加,131Ⅰ类放射性药品在生产、储存、使用及废物处置等过程中不可避免地产生放射性污染物,而放射性碘对人体健康和环境危害巨大,因此对碘核素的高效捕集具有重要意义.本文首先介绍了 131Ⅰ的主要来源和现有的捕集方法,随后详细介绍了近十年来不同类型的金属-有机骨架(MOFs)材料,包括 Cu-MOFs、Zn-MOF、Co-MOFs、Zr-MOFs、Al-MOFs、Ni-MOFs、Th-MOFs 和Cd-MOFs等材料,在吸附捕集放射性碘核素方面的研究进展,最后讨论并展望了未来应用MOFs材料工业化吸附捕集放射性碘核素存在的问题与挑战.
Recent Research Advancements in Metal-organic Frameworks for Radioiodine Adsorption
The foundation of nuclear medicine diagnosis and therapy is radioisotopes,such as 99Tc,131Ⅰ,137Cs,and 192Ir.However,the radioactive pollutants are inevitably produced during their production,storage,usage,and waste disposal steps.For example,131Ⅰ tends to accumulate and becomes concentrated in the thyroid gland,which can seriously affect human metabolic processes.Therefore,the safe disposal of the radioactive waste is desirable.This review summarizes the recent research advances of iodine adsorption over MOFs based on metal centers and provides a brief outline of the most prominent examples,including Cu-MOFs,Zn-MOFs,Co-MOFs,Zr-MOFs,Al-MOFs,Ni-MOFs,Th-MOFs and Cd-MOFs.In addition,the major challenges and prospects of the use of MOFs in handling radionuclide issues are also discussed.

Nuclear medicineMetal-organic frameworksRadioactive iodineAdsorption

彭丽、梁宇、陈婷、刘四斌、段崇雄

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长江大学附属荆州医院放射科,湖北荆州 434023

佛山大学材料与能源学院,广东佛山 528231

放射性碘核素 捕集方法 金属-有机骨架材料 高效吸附捕集

2024

标记免疫分析与临床
中国同辐股份有限公司

标记免疫分析与临床

CSTPCD
影响因子:0.978
ISSN:1006-1703
年,卷(期):2024.31(11)