18F-FDG PET/CT Manifestations of Blasticplasmacytoid Dendritic Cell Neoplasm:a Case Report
Objective To explore the PET/CT imaging manifestations of Blastic plasmacytoid dendritic cell neoplasm(BPDCN).Methods A retrospective analysis of the clinical and imaging examination results of a BPDCN patient diagnosed by immunohistochemical method was conducted to evaluate the 18F-FDG PET/CT imaging performance of BPDCN.Results The patient initially presented with skin tumors,accompanied by multiple purplish-red skin rashes and lymph node enlargement.The 18F-FDG PET/CT results showed as follows:①Diffusely increased FDG metabolism in the bone marrow with focally significant increased FDG metabolism,without obvious bone destruction;② Extensive distribution of enlarged lymph nodes with increased FDG metabolism throughout the body;③Diffusely increased FDG metabolism in the liver and spleen with an abnormally high metabolic nodule in the spleen;④Multiple thickened areas in the chest wall skin with slightly increased FDG metabolism.Bone marrow biopsy and immunohistochemical analysis were consistent with BPDCN.Conclusion BPDCN often presents with skin lesions as the initial symptom and tends to extensively involve the bone marrow and other organs.18 F-FDG PET/CT generally manifests as diffusely increased FDG uptake in multiple tissues and organs with local abnormal uptake,and the diagnosis relies on results of immunohistochemical analysis.
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