TAFRO syndrome with massive ascites and multiple system involvement:a case report and literatures review
Objective To explore the identification and clinical manifestations of TAFRO syndrome patients with massive ascites and multiple system involvement.Methods A patient with massive ascites and multiple system injuries in Aerospace Center Hospital in November 2015 was selected,and the admission data,clinical manifestations and laboratory examination results were analyzed retrospectively,and the related literatures were reviewed.Results The patient was a 39 years old female with acute onset and accompanied by massive ascites after fever,anemia,thrombocytopenia,increased SCr and oliguria.Physical examination showed that yellow staining of the skin and sclera,abdominal distension,no tenderness and rebound pain,positive shifting dullness,weak bowel sounds,an abdominal drainage tube with bloody drainage in the lower right abdomen,and lower limb edema.Laboratory test showed that WBC 8.45×109/L,RBC 1.73×1012/L,Hb 53g/L,PLT 11×109/L,BUN 51.6 mmol/L,SCr 232.9 μmol/L,Immunoglobulin G 1 730 mg/dl(normal range 751-1 560 mg/dl),lactate dehydrogenase 569.0 IU/L.Diagnosis of TAFRO syndrome was considered.The patient was given renal replacement and supportive treatment,combined with immunosuppressants,and the patient's clinical symptoms improved.Conclusions TAFRO syndrome has the same background as some autoimmune diseases,with clinical manifestations of multiple system involvement,acute onset,rare occurrence,difficult differentiation,and dangerous prognosis.Patients need emergency medical treatment and can achieve good clinical outcomes.
TAFRO syndromeascitesmultiple system involvementthrombocytopeniaanaemia
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