A study on the current status and influencing factors of the quality of life in patients with obstructive sleep apnea during the first and second trimester of pregnancy
Objective To explore the effects of obstructive sleep apnea (OSA) on the quality of life (QOL) during the first and second trimester of pregnancy.Methods Women in the first and second trimester of singleton pregnancy in Beijing Obstetrics and Gynecology Hospital,Capital Medical University from September 2020 to March 2022 were selected.QOL was assessed using the short form 36 health survey (SF-36) according to apnea hypopnea index (AHI).The relationship between the total score and each dimension score of SF-36 and the parameters of sleep monitoring,BMI and age were compared.Results A total of 171 women in the first and second trimester of singleton pregnancy were enrolled,aged from 25 to 45 years,with an average of (34.0±3.9) years.The total score of SF-36 was negatively correlated with the maximum duration of apnea during non rapid eye movement (NREM) sleep,bodily pain was negatively correlated with the average duration of apnea during NREM,and vitality was negatively correlated with the maximum oxygen deoxygenation time.Age had no significant effect on QOL,but BMI was negatively correlated with physical function.Conclusions OSA has a certain impact on QOL of pregnant women,and obesity can significantly affect QOL of pregnant women with OSA.Clinicians should attach more attention to QOL of OSA patients during pregnancy and provide corresponding lifestyle and psychological intervention,while paying attention to maternal and infant complications and outcomes.Compared with AHI,apnea hypopnea duration has a greater impact on QOL in pregnant women with OSA.In clinical practice,AHI,lowest oxygen saturation level and apnea hypopnea duration can be considered comprehensively to provide a new idea for the evaluation of OSA patients.
obstructive sleep apnea (OSA)quality of life (QOL)pregnancythe first and second trimesterspolysomnographySF-36 scaleobesity