Objective To explore the correlation between the reproductive characteristics of postmenopausal women and osteoporosis (OP) and sarcopenia in Beijing.Methods A total of 827 postmenopausal women who were permanent residents of several communities in different urban areas from September 2017 to May 2018 were selected,and were divided into non-OP group (n=488) and OP group (n=339) according to the results of bone mineral density measurement,and were divided into non-sarcopenia group (n=698) and sarcopenia group (n=129) according to the results of grip strength measurement.Their menstrual history,menopause history,pregnancy history and other related data were collected by on-site questionnaires.Serum 25(OH)D level was quantitatively measured by enzyme-linked immunosorbent assay,bone mineral density of lumbar spine and double hip joints was measured by dual-emission X-ray absorptiometry,and grip strength was measured by hand-held electronic grip strength meter.The influencing factors of OP and sarcopenia in postmenopausal women in Beijing were analyzed by multivariate logistic regression equation.Results Among 827 postmenopausal women,aged 46-85 years,with an average of (65.0±7.6) years.Among them,339 cases were OP (40.99%) and 129 cases were sarcopenia (15.60%).Multivariate logistic regression analysis showed that postmenopausal women with shorter menstrual duration (OR=0.930,95%CI:0.909-0.951,P<0.001),later menopause stage (OR=2.442,95%CI:1.964-3.307,P<0.001),more pregnancies (OR=2.335,95%CI:1.202-4.616,P=0.013),more births (OR=2.056,95%CI:1.945-2.713,P<0.001) and lower vitamin D level (OR=0.909,95%CI:0.903-0.916,P=0.001) had higher risk of OP.Postmenopausal women with more pregnancies (OR=1.309,95%CI:1.195-1.434,P<0.001),more births (OR=2.657,95%CI:2.064-3.421,P<0.001) and lower vitamin D levels (OR=0.623,95%CI:0.466-0.833,P=0.001) had higher risk of sarcopenia.Conclusions OP is common in postmenopausal women in Beijing.We should pay attention to the menstrual duration,menopause stage,pregnancy and childbirth times and vitamin D level of postmenopausal women,and do early screening to reduce or delay the occurrence of OP and sarcopenia.
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