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婴儿重症百日咳发生的影响因素分析

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目的 探讨婴儿重症百日咳发生的影响因素.方法 选取2020年1月至2022年12月银川市妇幼保健院百日咳婴儿224例,根据是否发生重症百日咳分为重症百日咳组(36例)和非重症百日咳组(188例).采用多因素logistic回归分析婴儿重症百日咳发生的影响因素.结果 224例百日咳婴儿中,男106例,女118例,年龄30~348 d,平均(113±56)d,重症百日咳发生率为16.1%.多因素logistic回归结果显示,年龄越小(OR=1.045,95%CI:1.010~1.082,P=0.011)、未接种百日咳疫苗(OR=6.705,95%CI:4.453~8.957,P=0.012)、呼吸做功增加(OR=15.471,95%CI:13.081~17.860,P=0.025)的婴儿发生重症的风险越高.结论 年龄小、未接种百日咳疫苗及呼吸做功增加是婴儿重症百日咳发生的危险因素.
Analysis of influencing factors of severe pertussis in infants
Objective To explore the influencing factors of severe pertussis in infants.Methods A total of 224 pertussis infants in Yinchuan Women and Children Healthcare Hospital from January 2020 to December 2022 were selected,and were divided into severe pertussis group (36 cases) and non-severe pertussis group (188 cases).The influencing factors of severe pertussis in infants was analyzed by multivariate logistic regression.Results Among 224 pertussis infants,there were 106 males and 118 females,aged from 30 to 348 days,with an average of (113±56) days.Multivariate logistic regression analysis showed that the younger age (OR=1.045,95%CI:1.010-1.082,P=0.011),the infants who had not been vaccinated with pertussis vaccine (OR=6.705,95%CI:4.453-8.957,P=0.012) and the infants who had increased respiratory work (OR=15.471,95%CI:13.081-17.860,P=0.025) had higher risk of severe illness.Conclusions Younger age,not vaccinated with pertussis vaccine and increased respiratory work are the risk factors for severe pertussis in infant.

pertussisinfantsevere pertussisinfluencing factors

王永明、吴梦思、罗靖侠、马静

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750000 银川市妇幼保健院新生儿科

百日咳 婴儿 重症百日咳 影响因素

宁夏自然科学基金

2022AAC03747

2024

北京医学
中华医学会北京分会

北京医学

CSTPCD
影响因子:0.714
ISSN:0253-9713
年,卷(期):2024.46(6)