首页|2014-2023年中国肠外营养处方中电解质补充的文献分析

2014-2023年中国肠外营养处方中电解质补充的文献分析

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目的 了解我国肠外营养(parenteral nutrition,PN)处方中电解质的补充情况.方法 以"肠外营养""静脉营养""处方分析""合理用药""医嘱分析"为关键词,检索2014-2023年中国知网和万方数据库发表的有关PN处方的相关文献,对纳入文献中电解质的使用情况进行分析.结果 共纳入文献99篇(成人85篇、新生儿14篇),涉及处方839 026份(成人810 870份、新生儿28 219份).99篇文献中,86篇文献(成人72篇、新生儿14篇)明确PN处方中补充了电解质,涉及处方750 874份(89.49%).72篇成人PN相关文献中,16篇文献明确了PN中阳离子制剂品种补充情况,其中10篇(62.5%)文献同时补充4种阳离子;810 807份成人PN处方中722 655份(89.13%)补充了电解质,其中6 261份(0.87%)处方的电解质补充存在稳定性超量;70篇(97.22%)文献未定期监测电解质补充情况.14篇新生儿PN处方相关文献中,仅7.1%(1/14)文献同时补充4种阳离子;28 219份新生儿PN处方(100%)均补充电解质,其中516份(1.83%)处方存在稳定性超量.结论 我国PN处方中电解质规范使用的比例偏低,表现为PN处方未添加电解质、或电解质补充超量,电解质制剂选择不规范等.建议规范PN处方中电解质补充,并定期监测电解质浓度.
Literature analysis of electrolyte supplement in parenteral nutrition prescriptions in China from 2014 to 2023
Objective To understand the status of electrolyte supplement in parenteral nutrition(PN)prescription in China.Methods"Parenteral nutrition""intravenous nutrition""prescription analysis""rational drug use""analysis of medical order"were taken as keywords,reletvant literatures about the rationality analysis of PN prescriptions published from CNKI and Wanfang databases from 2014 to 2023 were selected,and the utilization of electrolyte included in literatures were analyzed.Results A total of 99 literatures(85 for adults and 14 for newborns)were included,involving a total of 839 026 prescriptions(810 870 for adults and 28 219 for newborns).Among the 99 literatures,86 literatures(72 for adults and 14 for newborns)confirmed that electrolyte was supplemented in PN prescriptions,involving 750 874 prescriptions(89.49%).Of the 72 adult PN literatures,16 literatures defined the variety supplement of cationic preparations,of which 10(62.5%)literatures supplemented four cations at the same time;while among the 810 807 adult PN prescriptions,722 655(89.13%)were supplemented with electrolytes,of which 6 261(0.87%)prescriptions were supplemented with electrolytes with excessive stability,and electrolyte replenishment was not regularly monitored in 70 literatures(97.22%).Of the 14 neonatal literatures,only 7.1%(1/14)confirmed supplement of four cations at the same time,while among the 28 219 neonatal PN prescriptions,28 219(100%)were supplemented with electrolytes,of which 516 prescriptions(1.83%)had excessive stability.Conclusions The proportion of standardized use of electrolytes in PN prescription in China is low,which is manifested by the fact that there is no electrolyte added in PN prescription,or the electrolyte is over-supplemented,and the selection of electrolyte is not standardized.It is suggested that the electrolyte supplement in PN prescription should be standardized and the electrolyte situation should be monitored regularly.

nutritional support therapyparenteral nutrition(PN)electrolyterational drug useprescription

陈莲珍、范琳琳、江华、朱明炜、陈伟

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100021 北京,国家癌症中心国家肿瘤临床医学中心中国医学科学院北京协和医学院肿瘤医院药剂科

四川省医学科学院四川省人民医院(电子科技大学附属医院)急诊医学与灾难医学研究所

北京医院临床营养科

中国医学科学院北京协和医院临床营养科

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营养支持治疗 肠外营养 电解质 合理用药 处方

2024

北京医学
中华医学会北京分会

北京医学

CSTPCD
影响因子:0.714
ISSN:0253-9713
年,卷(期):2024.46(11)