Predictive value of lung ultrasound score and serum procalcitonin on prognosis of patients with severe pneumonia
Objective To evaluate the predictive value of lung ultrasound score(LUS)and serum procalcitonin(PCT)on prognosis of patients with severe pneumonia.Methods A total of 71 patients with severe pneumonia admitted to the Critical Care Unit of Beijing Electric Power Hospital from September 2020 to April 2023 were selected and were followed up for 28 d,the patients were divided into death group and survival group according to the prognosis of patients.The general data and clinical data of patients were collected,the influencing factors of prognosis of severe pneumonia were analyzed by multivariate logistic regression analysis equation,and the predictive value of LUS and PCT for the prognosis of patients with severe pneumonia was evaluated by ROC curve.Results Of the 71 patients,38 were males and 33 were females,aged from 47 to 91 years,with an average age of(72.8±10.8)years.After 28 d of follow up,17 cases(23.94%)died.Multivariate regression analysis results showed that severe pneumonia patients with higher LUS(OR=1.371,95%CI:1.131-1.663,P=0.001)and higher PCT(OR=1.104,95%CI:1.017-1.198,P=0.017)were more likely to die.The AUC of ROC for LUS and PCT for predicting the death of severe pneumonia patients were 0.804(95%CI:0.655-0.953,P<0.001)and 0.812(95%CI:0.708-0.916,P<0.001)respectively,and the cut-off value were 11 points for LUS and 0.8 ng/ml for PCT,respectively,while the sensitivity was 0.870 and 0.704,and the specificity was 0.706 and 0.882 respectively.Conclusions LUS and PCT can effectively predict the prognosis of patients with severe pneumonia.For patients with LUS>11 and/or PCT>0.8 ng/ml,we should pay close attention on the changes of respiratory function of the patients,apply antibiotics accurately when necessary,give respiratory support and protect organ function to improve the prognosis of patients.
万方数据
维普
