Efficacy of subcutaneous embedding acupuncture therapy on chemotherapy-induced nausea and vomiting in children with soft tissue sarcoma
白志媛 1王巍 1蒋文娇 1尤圣杰 2胡艳2
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作者信息
1. 国家儿童医学中心首都医科大学附属北京儿童医院护理部,北京 100045
2. 国家儿童医学中心首都医科大学附属北京儿童医院中医科,北京 100045
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摘要
目的 观察揿针疗法防治软组织肉瘤(soft tissue sarcoma,STS)患儿化疗所致恶心呕吐(chemotherapy-induced nausea and vomting,CINV)的效果.方法 选取2021年5月—2022年5月首都医科大学附属北京儿童医院肿瘤内科病房收治的STS患儿74例,按照随机数字表法将患儿分为试验组和对照组各37例.2组均接受长春新碱+阿霉素+环磷酰胺(vincristine+doxorubicin+cyclophosphamide,VDC)方案化疗,试验组在上述化疗基础上加揿针治疗.对比2组化疗第1、2天CINV发生情况和生活功能指数量表(functional living index-emesis,FLIE)评分.结果 与对照组比较,试验组化疗第1、2天恶心、呕吐严重程度更低(P<0.05),化疗期间FLIE评分高(P<0.05).结论 揿针疗法可减少STS患儿化疗所致CINV的发生,提高患儿化疗期间的生活质量.
Abstract
Objective To explore the efficacy of subcutaneous embedding acupuncture therapy on chemotherapy-induced nausea and vomiting in children with soft tissue sarcoma(STS). Methods 74 children with STS who were admitted into the Oncology ward of our hospital from May 2021 to May 2022 were selected and were divided into control group and experimental group by random number table. All children underwent vincristine+ doxorubicin+ cyclophosphamide (VDC) treatment. The control group (37 cases) was treated with routine western medicine ondansetron hydrochloride injection with intravenous injection for antiemetic treatment. The experimental group (37 cases) was treated with external treatment of traditional Chinese medicine for subcutaneous embedding acupuncture therapy on the basis of western medicine antiemetic treatment in the control group. The chemotherapy-induced nausea and vomting(CINV) on day 1 and day 2 and functional living index-emesis(FLIE) of 2 groups before and after intervention were collected and compared. Results Compared with the control group, the severity of nausea, vomiting in the experimental group on chemotherapy d1 and d2 were significantly reduced (P<0.05). Compared with the control group, the FLIE of the experimental group during chemotherapy was significantly higher (P<0.05). Conclusion Subcutaneous embedding acupuncture therapy can significantly reduce the occurrence of CINV and improve FLIE in children with soft tissue sarcoma.
关键词
软组织肉瘤/儿童/揿针/化疗/恶心呕吐
Key words
Soft tissue sarcoma/children/subcutaneous embedding acupuncture/chemotherapy/nausea and vomiting
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