Fuyuan Huoxue Decoction combined with percutaneous kyphoplasty in the treatment of 32 cases of thoracolumbar vertebral compression fractures
Objective To investigate the clinical effect of Fuyuan Huoxue Decoction combined with percutaneous kyphoplasty (PKP) in the treatment of thoracolumbar compression fractures. Methods A total of 64 patients with thoracolumbar vertebral compression fractures,who visited Department of Orthopedics,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University from November 2020 to November 2021,were divided into experimental group and control group by block randomization method. 32 patients in the control group were treated with PKP surgery,and 32 in the experimental group was treated with Fuyuan Huoxue Decoction orally for one week on the basis of the control group. The clinical efficacy,visual analogue scale (VAS),Oswestry dysfunction index (ODI) score,TCM syndrome score,the height of anterior and midline of injured vertebra were compared between the two groups.Results The effective rate of the experimental group was 25.00% (8/32),which was significantly higher than that of the control group,0.00% (0/32),and the difference was statistically significant (P<0.05). There was no significant difference in the total effective rate between the two groups (P>0.05). After one week of treatment,VAS and ODI scores of the two groups of patients were significantly lower than those before treatment (P<0.05),and the scores of the experimental group were significantly lower than those of the control group,and the difference was significant (P<0.05). After treatment,the scores of TCM syndromes in both groups were lowered than those before treatment(P<0.05),and the scores of TCM syndromes in the observation group were lowered than those in the control group (P<0.05). The height of the anterior edge of the injured vertebrae and the height of the midline of the injured vertebrae in the two groups were higher than those before treatment (P<0.05),while the recovery degree of the injured vertebral height in the experimental group was not significantly different from that in the control group (P>0.05). Conclusion Fuyuan Huoxue Decoction combined with PKP is effective in the treatment of thoracolumbar compression fractures,which can significantly reduce pain,help promote the recovery of lumbar vertebtral function and alleviate clinial symptoms.
Fuyuan Huoxue Decoctionpercutaneous kyphoplastythoracolumbar compression fracturesvertebral body heightlumbar function