从"肾虚血瘀"论治多系统萎缩
Treatment of multiple system atrophy through the lens of kidney deficiency and blood stasis
黄香香 1许红 2柴利香 1张晨晖 1袁有才2
作者信息
- 1. 陕西中医药大学 咸阳 712046
- 2. 陕西中医药大学附属医院
- 折叠
摘要
多系统萎缩是一组成年期发病、散发性的神经系统变性疾病.中医认为其核心病机为本虚标实,以肝脾肾亏虚为本,气、血、水湿运化失调为标,临床多从肝肾亏虚、脾肾亏虚和痰瘀互阻论治.肾虚血瘀为多系统萎缩主要病机,肾虚是多系统萎缩的根本病机,贯穿疾病始终,是治疗的关键.久病入络,瘀血既是多系统萎缩的病理产物,也是多系统萎缩的致病因素.多系统萎缩作为一个慢性进展性疾病,在相对较长的病程中均呈现本虚标实证,临床治疗应重视标本兼治、补肾活血.六味地黄汤补肾固本,四物汤活血化瘀以治标,二者相伍标本兼治,可明显改善多系统萎缩患者的语言及肢体功能.结合临床验案阐述从"肾虚血瘀"论治多系统萎缩的思路.
Abstract
Multiple system atrophy is a chronic and sporadic neurodegenerative disease. Traditional Chinese Medicine (TCM) considers its core pathogenesis to be rooted in deficiency of the liver,spleen,and kidney,with qi,blood,and fluid transportation and transformation imbalance as secondary characteristics. Clinical approaches often focus on treating liver and kidney deficiency,spleen and kidney deficiency,and the mutual obstruction of phlegm and blood stasis. Kidney deficiency and blood stasis are central pathogenic factors in multiple system atrophy. Kidney deficiency persists throughout the disease course and is crucial for treatment. Chronic progression of the disease involves blood stasis as both a pathological manifestation and a causative factor. As a chronic progressive disease,multiple system atrophy consistently presents patterns of deficiency and excess. Clinical treatment strategies emphasize addressing both symptoms and underlying causes,specifically through kidney supplementation and blood circulation promotion. Liuwei Dihuang Decoction (Six Ingredients Rehmannia Decoction) strengthens the kidneys and consolidates the foundation,while Siwu Decoction (Four Substances Decoction) promotes blood circulation and dispels stasis,effectively improving language and limb functions in multiple system atrophy patients. This paper discusses treating multiple system atrophy through the lens of kidney deficiency and blood stasis,supported by clinical cases.
关键词
多系统萎缩/肾虚血瘀/补肾活血Key words
multiple system atrophy/kidney deficiency and blood stasis/supplementing the kidney and promoting blood circulation引用本文复制引用
基金项目
陕西省自然科学基础研究计划项目(2022JM-470)
陕西省自然科学基础研究计划项目(2021JM-483)
咸阳市中医药科研项目(2023-113-1)
陕西中医药大学研究生质量提升工程专项项目(CXSJ202323)
出版年
2024
国家科技期刊平台
NSTL
万方数据