摘要
目的:研究内窥镜辅助龈下刮治联合赤藓糖醇龈下喷砂技术治疗种植体周围炎的临床疗效,为种植体周围炎的有效治疗提供理论依据.方法:选择本院牙周科就诊并接受治疗的种植体周围炎患者,按就诊时间共有58例种植体周围炎患者陆续进入观察,按随机数字表法分为对照组(28例)和微创组(30例);对照组患者采用传统盲视龈下刮治治疗,微创组患者采取内窥镜辅助龈下刮治联合赤藓糖醇龈下喷砂治疗.分析2组患者治疗前后探诊深度(PD)、改良菌斑指数(mPLI)和改良龈沟出血指数(mSBI)以及龈沟液中白细胞介素1β(IL-1β)、白细胞介素6(IL-6)和肿瘤坏死因子α(TNF-α)水平.结果:治疗前2组患者PD、mPLI和mSBI及龈沟液中IL-1β、IL-6和TNF-α水平比较差异无统计学意义(P>0.05),具有可比性.治疗后 2 组患者PD、mPLI和mSBI,龈沟液中IL-1β、IL-6和TNF-α水平均较治疗前明显下降(P<0.05).与对照组比较,微创组患者治疗后PD、mPLI和mSBI明显降低(P<0.05);龈沟液中IL-1β、IL-6和TNF-α水平也明显降低(P<0.05).结论:在短期内采用内窥镜辅助龈下刮治联合赤藓糖醇龈下喷砂技术治疗种植体周围炎更有助于控制种植体周围组织的炎症,改善临床症状.
Abstract
Objective:To study the clinical efficacy of endoscopic-assisted subgingival scaling combined with erythritol subgingival sand blasting technology for the treatment of peri-implantitis,and to provide the theoretical basis for the effective treatment of peri-implantitis.Methods:The patients with peri-implantitis who attended the Periodontology Department in our hospital and received treatment were selected.A total of 58 peri-implantitis patients were sequentially observed according to the time of visit and were randomly divided into control group(28 cases)and minimally invasive group(30 cases);the patients in control group underwent traditional blind subgingival curettage,while the patients in minimally invasive group were received endoscopic-assisted subgingival scaling combined with erythritol subgingival sandblasting.The probing depth(PD),modified plaque index(mPLI),modified sulcus bleeding index(mSBI),and levels of interleukin-1β(IL-1β),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α)in gingival crevicular fluid of the patients in two groups were analyzed before and after treatment.Results:Before treatment,there were no significant differences in PD,mPLI,mSBI,and levels of IL-1β,IL-6,and TNF-α in gingival crevicular fluid of the patients between two groups(P>0.05),demonstrating there was comparability.Compared with before treatment,the PD,mPLI,mSBI,and levels of IL-1β,IL-6,and TNF-α in gingival crevicular fluid of the patients in two groups after treatment were decreased(P<0.05).Compared with control group,the PD,mPLI,and mSBI of the patients in minimally invasive group were obviously decreased(P<0.05),and the levels of IL-1 β,IL-6,and TNF-α were also significantly decreased(P<0.05).Conclusion:In the short term,endoscopic-assisted subgingival scaling combined with erythritol subgingival sandblasting technology for the treatment of peri-implantitis is more beneficial in controlling inflammation around the peri-implant tissue and improving clinical symptoms.
基金项目
吉林省科技厅科技发展计划项目(20200403093SF)
吉林省科技厅科技发展计划项目(20210203090SF)
吉林省教育厅科学技术研究项目(JJKH20231234KJ)