Research Advances of Tachykinin-related Peptides and Receptors in Insect
Tachykinins belong to neuronal polypeptide family with various biological active functions. This family is well conserved in evolutionary process. Insect tachykinin-related peptides (TKRPs) have certain similarity with sequence structure of tachykinins, being peptide neurotransmitter as well. It is mainly expressed in the brain and intestinal tissue of insect, and regulate a series of intracellular signal pathway through receptor and ligand interaction and thus to yield various biological effects. This article focuses on the finding of tachykinin receptors in the silkworm, Bombyx mori, and summarizes the advances in the signal transduction via the analysis of receptor-ligand interaction.
Tachykinin-related peptideTachykinin receptorInsectBombyx mori