Reconstruction of Chinese materia medica-debark peony root
Through the investigation of ancient books and the sorting of the modern research achievements of traditional Chinese medicine,combined with the understanding and application experience of well-known experts and scholars in desciplinary fields such as traditional Chinese medicine clinical medicine and science of Chinese materia medica,it is concluded that debark peony root mainly has the effects of nourishing and constraining blood,softening liver for relieving pain,and calming liver yang.The symptom targets are abdominal pain,muscle spasm,and hypochondriac pain.Modern pharmacological studies have found that debark peony root and its active ingredient,namely total glucosides of debark peony root have the effects of anti-inflammatory,spasmolysis,analgesia,bacteriostasis,defaecation,alleviating acute liver injury,and immunomodulatory.Long-term toxicity experiments of debark peony root and its main component,total glucosides of debark peony root,do not find any toxicity to humans or animals,and the safety range is large.The clinical dose is 6-120 g.When taken orally,it should be used dialectically according to different diseases or different stages of the same disease,and the construction of dose-effect relationship between the dosage of debark peony root and the symptom target should be explored actively.
debark peony rootsymptom targetreconstruction of Chinese materia medicaclinical verification