Value of F-deoxyglucose positron emission tomography imaging in the differential diagnosis of liver metastases from colorectal cancer and primary liver cancer
Objective To explore the value of F-deoxyglucose positron emission tomography(PET)imaging in the differential diagnosis of liver metastases from colorectal cancer and primary liver cancer.Methods The clinical data of 76 patients with liver metastases from colorectal cancer and 82 patients with primary liver cancer admitted to Fudan University Shanghai Cancer Center from June 2020 to May 2022 were analyzed retrospectively.They were designated as colorectal cancer with liver metastasis group and primary liver cancer group respectively.All patients underwent F-deoxyglucose PET imaging.The clinical data and related parameters of F-deoxyglucose PET imaging[maximum standardized uptake value(SUVmax),total glycolysis(TLG),metabolic tumor volume(MTV)]of two groups were compared.Logistic regression analysis was used to analyze the related factors influencing the differential diagnosis of liver metastases from colorectal cancer and primary liver cancer.Receiver operating characteristic(ROC)curve was made to analyze the value of F-deoxyglucose PET imaging in the differential diagnosis of liver metastases from colorectal cancer and primary liver cancer.Results The levels of carcinoembryonic antigen(CEA),alpha fetoprotein(AFP),alpha fetoprotein heterogeneity(AFP-L3),TLG and MTV in colorectal cancer with liver metastasis group were higher than those in primary liver cancer group(P＜0.05).The results of multivariate analysis showed that TLG and MTV were the relevant factors influencing the differential diagnosis of liver metastases from colorectal cancer and primary liver cancer(P＜0.05).ROC curve analysis showed that TLG,MTV,and their combination had higher diagnostic efficacy in differential diagnosis of liver metastases from colorectal cancer and primary liver cancer.Conclusion Related parameters of F-deoxyglucose PET imaging(TLG and MTV)have higher diagnostic efficacy in the differential diagnosis of liver metastases from colorectal cancer and primary liver cancer.
万方数据
维普
