Effect of Sanwu capsules on clinical efficacy and neurological functional recovery in patients with stroke sequelae
Objective To explore the effect of Sanwu capsules on clinical efficacy and neurological functional recovery in patients with stroke sequelae.Methods 106 patients with stroke sequelae admitted to Xiangya Hospital of Central South University from March 2020 to September 2022 were randomly divided into the Western medicine group(53 cases)and the combined Chinese medicine group(53 cases).The Western medicine group was treated with aspirin,and the combined Chinese medicine group was treated with aspirin plus Sanwu capsules.Clinical efficacy,the scores of traditional Chinese medicine syndrome,levels of serum cytokines,hemorheology indexes,neurological function and quality of life of two groups were statistically analyzed.Results After 4 weeks of treatment,the total effective rate of the combined Chinese medicine group(90.57%,48/53)was higher than that of the Western medicine group(75.47%,40/53)(P<0.05).Compared with before treatment,after 4 weeks of treatment,the scores of traditional Chinese medicine syndrome,serum level of S100-β,hematocrit(HCT),plasma viscosity(PV),whole blood low shear viscosity(WBLSV),whole blood high shear viscosity(WBHSV),scores of National Institutes of Health Stroke Scale(NIHSS)and neurological deficits(NDS)decreased,and the combined Chinese medicine group was lower than the Western medicine group(P<0.05);The levels of serum brain-derived neurotrophic factor(BDNF),endothelium-derived hyperpolarization factor(EDHF)and nitric oxide(NO),and scores of Berg balance scale,lower-extremity Fugl-Meyer Assessment(FMA)and quality of life were all elevated in both groups,and the combined Chinese medicine group was higher than the Western medicine group(P<0.05).Conclusion Sanwu capsules can relieve the traditional Chinese medicine syndrome of stroke sequelae patients,improve the levels of serum cytokines and hemorheology,promote the recovery of nerve function and lower limb function,improve the quality of life of patients,and has the good therapeutic effect.
sequelae of strokeSanwu capsulesclinical effectneurological function
万方数据
维普
