Effect of staging acupuncture on ovarian function in patients with premature ovarian insufficiency based on the theory of transformation of waxing and waning of yin-yang
Objective To explore the effect of staging acupuncture on ovarian function in patients with premature ovarian insufficiency(POI)based on the theory of"transformation of waxing and waning of yin-yang".Methods 150 patients with POI of kidney deficiency and stagnation of liver qi type admitted to the outpatient department of Qionghai Hospital of Traditional Chinese Medicine from September 2019 to September 2022 were selected as the research subjects and divided into the control group(75 cases)and the observation group(75 cases)according to random number table method.The control group was treated with hormone replacement therapy,and the observation group was treated with staging acupuncture based on the theory of"transformation of waxing and waning of yin-yang".All patients were treated continuously for 3 menstrual cycles.The clinical efficacy after 3 menstrual cycles of treatment,the score of traditional Chinese medicine syndrome before treatment and after 1 and 3 menstrual cycles of treatment,and psychological state,the score of perimenopausal symptom,quality of sleep,quality of life and ovarian function before treatment and after 3 menstrual cycles of treatment of two groups were compared.Results After 3 menstrual cycles of treatment,the total effective rate in the observation group(96.00%,72/75)was higher than that in the control group(70.67%,53/75)(P<0.05).After 1 menstrual cycle of treatment,the scores of traditional Chinese medicine syndrome of two groups were lower than those before treatment;After 3 menstrual cycles of treatment,the scores of traditional Chinese medicine syndrome of two groups were lower than those before treatment and after 1 menstrual cycle of treatment;And after 1 and 3 menstrual cycles of treatment,the observation group was lower than the control group(P<0.05).Compared with before treatment,after 3 menstrual cycles of treatment,the scores of Self-rating Depression Scale(SDS),Self-rating Anxiety Scale(SAS),Modified Kupperman Index(KI)and Pittsburgh Sleep Quality Index(PSQI),and the levels of serum follicle-stimulating hormone(FSH)and luteinizing hormone(LH)in two groups decreased,and the observation group was lower than the control group;The score of quality of life scale-100(QOL-100),the levels of serum estradiol(E2)and anti-Mullerian hormone(AMH),total ovarian volume(TOV),and basic antral follicle count(AFC)in both ovaries increased,and the observation group was higher than the control group(P<0.05).Conclusion The staging acupuncture based on the theory of"transformation of waxing and waning of yin-yang"can effectively relieve the clinical symptoms of patients with POI of kidney deficiency and stagnation of liver qi type,recover the ovarian function of patients,help alleviate the negative psychological state of patients,improve the quality of sleep,and enhance the quality of life of patients.This therapy has good clinical efficacy.
premature ovarian insufficiencykidney deficiency and stagnation of liver qi typeacupunctureovarian function
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