Current status and progress of prediction methods for delayed encephalopathy after acute carbon monoxide poisoning
王霈雯 1滕登科 1谭诚 1刘俊志1
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作者信息
1. 吉林大学中日联谊医院,长春 130033
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摘要
急性一氧化碳中毒迟发性脑病(delayed encephalopathy after acute carbon monoxide poisoning,DEACMP)发病隐匿、病程较长、致残率高,主要表现为精神意识的障碍.尽管早期预测DEACMP的发生有助于改善预后、减少后遗症的发生,但如何对DEACMP进行准确的预测一直是临床上急需解决的难点问题.近年来,对DEACMP的预测从临床表现、实验室指标、神经电生理检查、影像学检查及遗传易感性等方面均取得了一定的进展,临床医生需要综合研判,预测迟发性脑病的发生,及时进行干预.
Abstract
Delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) is characterized by hidden onset,long course and high disability rate. The main manifestation of this disease is a disorder of mental consciousness. Although early prediction of the occurrence of DEACMP is helpful to improve prognosis and reduce the occurrence of sequelae,how to accurately predict DEACMP has always been a difficult problem that urgently needs to be solved in clinical practice. In recent years,some progresses have been made in the prediction of DEACMP in terms of clinical manifestations,laboratory indicators,neuroelectrophysiological examinations,imaging examinations and genetic susceptibility and so on. Clinicians need to make comprehensive researches and judgments,predict the occurrence of delayed encephalopathy,and intervene timely.
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