Clinical study on the auxiliary treatment of chronic obstructive pulmonary disease complicated with respiratory failure with traditional Chinese medicine enema using Yiqi Tongfu therapy
Objective To explore the therapeutic effect of traditional Chinese medicine enema with Yiqi Tongfu therapy on patients with chronic obstructive pulmonary disease(COPD)complicated with respiratory failure.Methods 82 COPD patients with respiratory failure were divided into the control group and the observation group according to random number table method,with 41 cases in each group.The control group was treated with non-invasive positive pressure ventilation and other Western medicine treatment on the basis of conventional Western medicine treatment,and the observation group was additionally treated with traditional Chinese medicine enema with Yiqi Tongfu therapy on the basis of the treatment of the control group.The changes of the lung function indicators,serum inflammatory indicators[tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),interleukin-8(IL-8)],blood gas analysis indicators[arterial partial pressure of oxygen(PaO2),oxygen saturation of blood(SaO2),partial pressure of carbon dioxide(PaCO2)],COPD Assessment Test(CAT)score,mMRC score,and the Body-Mass Index,Airflow Obstruction,Dyspnea,and Exercise Capacity Index(BODE)score before and after treatment in two groups were observed,and the total effective rate of treatment and incidence of adverse reactions between two groups were compared.Results After treatment,the lung function indicators,the levels of PaO2 and SaO2,and total effective rate in the observation group were higher than those in the control group(P<0.05),and the levels of TNF-α,CRP,IL-8 and PaCO2,and the CAT score,mMRC score and BODE score,and the total incidence of adverse reactions were lower than those in the control group(P<0.05).Conclusion The traditional Chinese medicine enema with Yiqi Tongfu therapy can improve lung ventilation function of COPD with respiratory failure,regulate blood gas analysis indicators,inhibit inflammatory reactions in the body,improve clinical prognosis of patients,and have fewer adverse reactions.
chronic obstructive pulmonary diseasetype Ⅱ respiratory failureblood gas analysis indicatorlung function