Study on the therapeutic effect of Kunning Jiigu formula in the treatment of postoperative osteoporosis of gynecological malignant tumors
Objective To explore the clinical efficacy of Kunning Jiigu formula in the treatment of postoperative osteoporosis of gynecological malignant tumors.Methods A total of 60 patients with gynecological malignant tumor who underwent postoperative folow-up were selected and randomly divided into the study group and the control group,with 30 cases in each group.The control group was treated with calcilic D,and the study group was treated with Kunning Jiangu prescription on the basis of the treatment of the control group.Traditional Chinese medicine(TCM)syndrome scores(waist and knee pain,dysphoria with feverish sensation in chest,dry eyes,preference for sighing,poor flexion and extension,skeletal muscle pain and discomfort,dizziness and tinnitus,dry mouth and pharyngeal xeransis,insomnia and dreaminess),the disappearance time of clinical symptoms(lower back pain,soreness and weakness of waist and knees,spasticity on lower limbs,trudge,difficulty holding heavy objects),pain degree,and levels of calcium and phosphorus metabolism indexes[blood calcium(Ca),phosphorus(P),alkaline phosphatase(ALP)]were observed of two groups before and after treatment.Clinical efficacy and incidence of adverse reactions of two groups were compared.Results After treatment,the scores of soreness and pain of waist and knees,dysphoria with feverish sensation in chest,dry eyes,preference for sighing,poor flexion and extension,skeletal muscle pain and discomfort,dizziness and tinnitus,dry mouth and pharyngeal xeransis,insomnia and dreaminess,and the disappearance time of lower back pain,soreness and weakness of waist and knees,spasticity on lower limbs,trudge and difficulty holding heavy objects,and bone density level of femoral neck and lumbar spine L1-L4,and pain degree,and the levels of Ca,P and ALP in the study group were superior to those in the control group(P＜0.05).No adverse reactions occurred in two groups during treatment.Conclusion Kunning Jiangu formula is effective and safe in the treatment of postoperative osteoporosis of gynecological malignant tumors,and can be widely promoted and applied in clinical practice.
万方数据
维普
