摘要
通过古籍文献调研、中医药现代研究成果的梳理,结合中医临床及中药学等学科领域内知名专家学者的认识及应用经验,归纳出薏苡仁:功效主要为健脾利湿、清热解毒、消肿排脓.症靶为腹泻、关节疼痛、化脓、痤疮、水肿.标靶为胃溃疡、胃肠道肿物、泌尿系感染.现代药理研究发现,薏苡仁及其有效成分具有降糖、降脂、消水肿、抗肿瘤、抗溃疡、止泻、抗炎镇痛、抗氧化、调节免疫等作用.薏苡仁属于药食同源类药物,毒性普遍较低.临床使用剂量为10～120 g,内服时当根据不同疾病,或同一疾病的不同阶段进行辨证使用,并积极探索薏苡仁用量与症靶、标靶的量效关系构建.
Abstract
Through investigation of ancient books and the sorting of the modern research achievements of traditional Chinese medicine,combined with the understanding and application experience of well-known experts and scholars in desciplinary fields such as traditional Chinese medicine clinical medicine and science of Chinese materia medica,it is concluded that coix seed mainly has the effects of invigorating spleen for eliminating dampness,clearing heat and removing toxicity,and detumescence and discharging pus.The symptom targets are diarrhea,joint pain,suppuration,acne,and edema.The biochemical indicator targets are gastric ulcers,gastrointestinal masses,and urinary tract infections.Modem pharmacological studies have found that coix seed and its active ingredients have hypoglycemic,lipid lowing,anthydropic,anti-tumor,antiulcer,anti-diarrhoeal,anti-inflammatory and analgesic,antioxidant,and immunoregulatory effects.Coix seed belongs to the homology of medicine and food,with generally low toxicity.The clinical dosage is 10-120g.When taken orally,it should be used dialectically according to different diseases or different stages of the same disease,and the construction of dose-effect relationship between the dosage of coix seed and the symptom target and biochemical indicator target should be explored actively.
基金项目
北京中医药大学壶天客座教授科研启动经费(2023-XJ-KYQD-006)
中国中医科学院优秀青年科技人才培养专项(ZZ13-YQ-026)
中央高水平中医医院临床研究和成果转化能力提升项目临床科研一体化人才专项(续航工程)(CZ40907)
维普
万方数据