Clinical efficacy of modified Radix Ophiopogon soup in the treatment of syndrome of deficiency of stomach yin after acute abdominal surgery
Objective To explore the clinical efficacy of modified Radix Ophiopogon soup on syndrome of deficiency of stomach yin after acute abdominal surgery and its influence on acute stress response.Methods 104 patients with syndrome of deficiency of stomach yin after acute abdominal surgery were selected and divided into the study group and the control group according to random number table method,with 52 cases in each group.The control group received conventional Western medicine treatment,and the study group received treatment with modified Radix Ophiopogon soup.Symptom relief time,traditional Chinese medicine(TCM)symptom score,clinical efficacy,levels of superoxide dismutase(SOD),glutathione peroxidase(GSH-Px),interleukin 1β(IL-1β)and tumor necrosis factor α(TNF-α),and occurrence of adverse reactions in both groups were compared.Results The recovery time of bowel sounds and postoperative body temperature,and postoperative anal exhaust time in the study group were shorter than those in the control group(P＜0.05).After treatment,the scores of abdominal distension,abdominal pain,constipation,anorexia,nausea and vomiting,red and dry tongue in both groups decreased(P＜0.05),and the study group was lower than the control group(P＜0.05).The total effective rate of the study group(94.23％,49/52)was higher than that of the control group(80.77％,42/52)(P＜0.05).After treatment,the levels of serum SOD and GSH-Px in two groups increased(P＜0.05),and the study group was higher than the control group(P＜0.05).After treatment,the levels of IL-1 β and TNF-α in two groups decreased(P＜0.05),and the study group was lower than the control group(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between two groups(P＞0.05).Conclusion The modified Radix Ophiopogon soup has the definite therapeutic effect on patients with syndrome of deficiency of stomach yin after acute abdominal surgery.This therapy can improve clinical symptoms,alleviate acute stress response of the patients,and is safe and reliable.
Radix Ophiopogon soupacute abdomensyndrome of deficiency of stomach yinstress response
万方数据
维普
