首页|2型糖尿病性视网膜病变住院患者中西医诊治特点分析

2型糖尿病性视网膜病变住院患者中西医诊治特点分析

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目的 探讨2型糖尿病性视网膜病变(T2DR)住院患者的诊治特点.方法 使用电子病历系统检索2010年1月-2016年4月江苏省中医院内分泌科住院治疗的T2DR患者相关临床信息,统计其一般人口学资料、合并症、生化指标、中西医治疗方案及专科检查情况,分析T2DR住院患者的诊治特点.结果 T2DR患者中糖尿病肾脏病(DKD)发生率最高(46.7%),合并疾病中高血压发生率最高(62.8%);增殖期糖尿病视网膜病变(PDR)合并T2DR患者中DKD、糖尿病足、高血压及高脂血症的发生率较非增殖期糖尿病视网膜病变(NPDR)显著升高(P<0.05).PDR患者三酰甘油(TG)、血清尿酸(SUA)、尿总蛋白定量及尿白蛋白/肌酐水平均显著高于NPDR患者(P<0.001);PDR患者胰岛素类似物、钙通道阻滞剂(CCB)、血管紧张素受体拮抗剂(ARB)及α受体阻滞剂的使用率显著高于NPDR(均P<0.005);PDR患者他汀类药物和醛糖还原酶抑制剂的使用率显著高于NPDR(均P<0.05).PDR患者益气化湿活血通络法使用率高于NPDR患者(P<0.05),滋阴清热和滋阴活血的使用率低于NPDR患者(均P<0.05).PDR患者的眼球超声检查率、全视网膜光凝术和玻璃体切除术的使用率均显著高于NPDR(P<0.001).结论 PDR患者胰岛素类似物、CCB、ARB、α受体阻滞剂、他汀类药物和醛糖还原酶抑制剂的使用率显著高于NPDR;PDR期益气化湿活血通络法的使用率明显高于NPDR.PDR患者应进一步提高眼底造影检查率,更好地评估病情.
Analysis of characteristics of diagnosis and treatment of type 2 diabetic retinopathy inpatients with Chinese and Western medicine
Objective To explore the characteristics of diagnosis and treatment of inpatients with type 2 diabetic retinopathy(T2DR).Methods The electronic medical record system was used to retrieve the relevant clinical information of T2DR inpatients in the department of endocrinology,Jiangsu Province Hospital of Traditional Chinese Medicine from January 2010 to April 2016.The general demographic data,complications,biochemical indicators,traditional Chinese and Western medicine treatment plans and specialized examinations were statistically analyzed,and characteristics of diagnosis and treatment of T2DR inpatients were analyzed.Results The incidence of diabetic kidney disease(DKD)was the highest in T2DR patients(46.7%),and the incidence of hypertension was the highest in the combined diseases(62.8%).The incidence of DKD,diabetic foot disease,hypertension and hyperlipidemia in patients with proliferative diabetic retinopathy(PDR)combined with T2DR was significantly higher than that in patients with non-proliferative diabetic retinopathy(NPDR)(P<0.05).The levels of triglyceride(TG),serum uric acid(SUA),urinary total protein and urinary albumin/creatinine in PDR patients were significantly higher than those in NPDR patients(P<0.001).The use rates of insulin analogues,calcium channel blockers(CCB),angiotensin receptor blockers(ARB)and α receptor blockers in PDR patients were significantly higher than those in NPDR patients(all P<0.005).The usage rates of statins and aldose reductase inhibitors in PDR patients were significantly higher than those in NPDR patients(all P<0.003).The usage rate of benefiting qi,eliminating dampness,promoting blood circulation for removing obstruction in collaterals method in PDR patients was higher than that in NPDR patients(P<0.05),while the usage rates of drugs that nourish yin and clear heat,and nourish yin and promote blood circulation in PDR patients were lower than those in NPDR patients(all P<0.05).The rates of eye ultrasound examination,and usage rates of panretinal photocoagulation,and vitrectomy in PDR patients were significantly higher than those in NPDR patients(P<0.001).Conclusion The usage rates of insulin analogues,CCB,ARB,α receptor blockers,statins and aldose reductase inhibitors in PDR patients are significantly higher than those in NPDR patients.The usage rate of benefiting qi,eliminating dampness,promoting blood circulation for removing obstruction in collaterals method in PDR patients is significantly higher than that in NPDR patients.The rate of fundus angiography should be further increased in PDR patients to better evaluate the disease.

type 2 diabetic retinopathycomplicationbiochemical indexbasic treatmentChinese medicine treatmentfundus examination

周雷、赵越

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南京中医药大学附属医院/江苏省中医院,南京 210029

2型糖尿病性视网膜病变 合并症 生化指标 基础治疗 中医治疗 眼底检查

江苏省自然科学基金项目

BK20191090

2024

长春中医药大学学报
长春中医药大学

长春中医药大学学报

CSTPCD
影响因子:0.916
ISSN:1007-4813
年,卷(期):2024.40(8)
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