Therapeutic effect of Furong Tongmai Capsule on primary hypertension with syndrome of internal binding of static blood
Objective To explore the clinical efficacy of Furong Tongmai Capsule on patients with primary hypertension with syndrome of internal binding of static blood.Methods 92 patients with primary hypertension with syndrome of internal binding of static blood were selected and divided into the control group and the observation group according to the method of random selection by drawing,with 46 cases in each group.The control group was treated with valsartan combined with the placebo,and the observation group was treated with valsartan combined with Furong Tongmai Capsules.Both groups were treated for 12 weeks.The clinical efficacy,traditional Chinese medical syndrome score,serum cytokine levels,dynamic blood pressure changes,hemorheology indexes and incidence of adverse reactions were compared between two groups.Results The total effective rate of the observation group(91.30%,42/46)was higher than that of the control group(71.74%,33/46)(P<0.05).After treatment,scores of various traditional Chinese medicine syndromes,serum insulin-like growth factor 1(IGF-1),angiotensin Ⅱ(AngⅡ)and aldosterone(ALD)levels,daytime systolic blood pressure(D-SBP),nighttime systolic blood pressure(N-SBP),24 hours systolic blood pressure(24h-SBP),daytime diastolic blood pressure(D-DBP),nighttime diastolic blood pressure(N-DBP),24 hours diastolic blood pressure(24h-DBP),and the levels of various hemorheology indexes decreased,and the observation group was lower than the control group(P<0.05).After treatment,the level of serum PRA in two groups increased,and the observation group was higher than the control group(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between two groups(P>0.05).Conclusion Furong Tongmai Capsules can effectively regulate the levels of cytokines in patients with primary hypertension with syndrome of internal binding of static blood,promote the reduction of blood pressure,and improve their hemorheology index levels and traditional Chinese medicine syndromes.This therapy has good therapeutic effect.
primary hypertensionsyndrome of internal binding of static bloodFurong Tongmai Capsulevalsartan
万方数据
维普
